# US 10,117,449 B2 · Extrusion process

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- Number: US 10,117,449 B2
- Document ID: US10117449B2
- Status: Granted
- Kind: B2
- Application number: 14/381,743
- Filed: 2013-02-27
- Published: 2015-02-26
- Granted: 2018-11-06
- Earliest claimed: 2012-02-28
- Assignees: Dsm IP Assets B.V.
- Applicants: Dsm IP Assets B.V.
- Inventors: Petrus Henricus Maria Elemans; Adrian Willem Meesen; Alexandra Teleki; Bruno Leuenberger
- Web page: https://patentgrep.com/patent/US10117449B2

## CPC

- A23L 27/70: {Fixation, conservation, or encapsulation of flavouring agents}
- A23D 7/0053: {Compositions other than spreads}
- A23D 7/04: Working-up
- A23K 20/10: Organic substances
- A23K 20/147: Polymeric derivatives, e.g. peptides or proteins
- A23K 20/158: Fatty acids; Fats; Products containing oils or fats
- A23K 20/163: Sugars; Polysaccharides
- A23K 20/174: Vitamins
- A23K 20/179: Colouring agents, e.g. pigmenting or dyeing agents
- A23K 40/20: by moulding, e.g. making cakes or briquettes
- A23K 40/25: by extrusion
- A23L 5/44: using carotenoids or xanthophylls
- A23L 29/212: Starch; Modified starch; Starch derivatives, e.g. esters or ethers (containing starch hydrolysates, e.g. dextrin, A23L29/30)
- A23L 33/15: Vitamins
- A23P 30/20: Extruding
- A61K 8/31: Hydrocarbons
- A61Q 19/00: Preparations for care of the skin
- A23V 2002/00: Food compositions, function of food ingredients or processes for food or foodstuffs
- A23L: FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF (preservation thereof A23B)
- A23D: EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS (preservation thereof A23B20/00; production, refinement or preservation of animal or vegetable fats or oils C11B, C11C)
- A23K: FODDER
- A23P: SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A23V: INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION

## Abstract

The present invention relates to a process for the production of extruded formulations (=extrudates) comprising dispersion droplets, to such formulations as well as to the use of such formulations in food, feed, personal care applications.

## Claims

### Claim 1

A process for production of an extrudate which comprises dispersion droplets, wherein the process comprises:
(i) introducing emulsion ingredients consisting of at least one carotenoid, modified food starch as an emulsifying protective colloid for the carotenoid, and water into at least one feed hopper of a nitrogen gas purged extruder having an extruder barrel and an extruder screw,
(ii) operating the extruder so as to emulsify the emulsion ingredients in the extruder barrel to thereby form an emulsified dispersion of dispersion droplets having an average droplet size (d3,2) between 50 nm and 1000 nm consisting of the carotenoid dispersed within the modified food starch as an emulsifying protective colloid for the carotenoid, and
(ii) extruding the emulsified dispersion consisting of the dispersion droplets dispersed within the modified food starch from the extruder barrel to form an extrudate which consists of the dispersion droplets dispersed within the modified food starch.

### Claim 2 (depends on 1)

The process according to claim 1, wherein the process is carried out in the absence of an organic solvent.

### Claim 3 (depends on 1)

The process according to claim 1, wherein the carotenoid is at least one selected from the group consisting of α-carotene, β-carotene, 8′-apo-β-carotenal, 8′-apo-β-carotenoic acid esters, canthaxanthin, astaxanthin, lycopene, lutein, zeaxanthin and crocetin.

### Claim 4 (depends on 1)

The process according to claim 1, wherein the carotenoid is β-carotene.

### Claim 5 (depends on 1)

The process according to claim 1, wherein the at least one carotenoid is present in step (i) in an amount of 0.5 wt-% 50 wt-%, based on the total weight of the extrudate.

### Claim 6 (depends on 1)

The process according to claim 1, wherein the modified food starch is present in step (i) in an amount of 5 wt-% 80 wt-%, based on the total weight of the extrudate.

### Claim 7 (depends on 1)

The process according to claim 1, wherein the water is present in step (i) in an amount of 1 wt-%-90 wt-%, based on the total weight of the extrudate.

### Claim 8 (depends on 7)

The process according to claim 7, wherein the water is present in an amount of 5 wt-%-30 wt-%, based on the total weight of the extrudate.

### Claim 9 (depends on 1)

The process according to claim 1, wherein the emulsion ingredients of step (i) further consist of 0.1 wt-%-50 wt-%, based on the total weight of the extrudate, of at least one auxiliary agent.

### Claim 10 (depends on 9)

The process according to claim 9, wherein the auxiliary agent is at least one selected from the group consisting of antioxidants, ethoxyquin, plasticisers, stabilisers, humectants, protective colloids without emulsifying properties, gelling agents, dyes, fragrances, fillers and buffers.

### Claim 11 (depends on 1)

The process according to claim 1, wherein the step (i) comprises sequentially adding to the extruder (1) the modified food starch as an emulsifying protective colloid for the at least one carotenoid, (2) the water and thereafter (3) the at least one carotenoid.

### Claim 12 (depends on 1)

The process according to claim 1, wherein the carotenoid is β-carotene, and wherein step (i) comprises adding the β-carotene in a molten form to the extruder in advance of the at least one emulsifying protective colloid and the water.

### Claim 13 (depends on 1)

The process according to claim 1, wherein the carotenoid is β-carotene, and wherein step (i) comprises adding the β-carotene to the extruder as a powder.

### Claim 14 (depends on 1)

The process according to claim 1, wherein the temperature inside the extruder is between 20° C. and 220° C.

### Claim 15 (depends on 1)

The process according to claim 1, wherein the total residence time for the ingredients is between 1 and 400 s.

### Claim 16 (depends on 13)

The process according to claim 13, wherein step (i) comprises adding the β-carotene to the extruder in a mixture with the modified food starch.

### Claim 17 (depends on 1)

A food, feed or personal care product which comprises an extrudate obtained by the process of claim 1.