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US 10,113,153 B2Granted
P450-BM3 variants with improved activity
AssigneeCodexis, Inc.
InventorsRobert Osborne, Vesna Mitchell, Khin Yu Naing Htwe, Xiyun Zhang, Erika M. Milczek, Jeffrey C. Moore
Life of this patent
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Abstract
The present invention provides improved P450-BM3 variants with improved activity. In some embodiments, the P450-BM3 variants exhibit improved activity over a wide range of substrates.
Claims9
A recombinant polynucleotide sequence encoding a recombinant cytochrome P450-BM3 variant, wherein said sequence comprises SEQ ID NO:
- 3, and further wherein said recombinant cytochromie P450-BM3 variant oxidizes at least three organic substrates.
Dependencies are inferred from the claim text.