Benzamide or benzamine compounds useful as anticancer agents for the treatment of human cancers

A compound according to Formula I-g

• wherein
• R1 is selected from the group consisting of
• n=0, 1, or 2;
• m=0 or 1;
• R2 and R3 can be attached at any available position on the aromatic ring and are independently selected from the group consisting of H, D, F, Cl, CF3, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C1-C6 hydroxyalkyl, cycloalkyl, OR, N(R)2, NO2, N3, NH—C(O)—R, CN, C(O)R, C(O)OR, C(O)N(R)2, SR, alkylacyl, and arylacyl;
• Each R is independently selected from the group consisting of H, C1-3 alkyl, propargyl, and phenyl;
• R4 and R5 are independently selected from the group consisting of H, C1-6 alkyl optionally substituted with N(R)2, C2-C6 alkenyl, C2-C6 alkynyl, C1-C6 hydroxyalkyl, phenyl optionally substituted with R3, and CH2OC(O)-phenyl optionally substituted with R3;
• R6 and R7 are independently selected from the group consisting of H, C1-3 alkyl, and C(O)OMe3;
• such that all possible stereoisomers, including optically active isomers, are included whenever stereogenic centers are present;
• or a pharmaceutically acceptable salt, prodrug, active metabolite, or solvate thereof.