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US 10,106,684 B2Granted
Method for making Schiff base
AssigneeKing Fahd University of Petroleum and Minerals
InventorAasif Helal
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Abstract
Fluorescent Schiff base compounds comprising a xanthene dye based moiety and an alkyl imidazole moiety. Methods of assessing these fluorescent Schiff base compounds as fluorescent probes for metal ions in Cu2+ chemosensing applications, methods of preparing the fluorescent Schiff base compounds and methods of detecting Cu2+ ions with the same are also provided.
Claims4
A method for making a Schiff base of formula (I)
- or a salt, solvate, tautomer, or stereoisomer thereof;
- wherein R1 is an optionally substituted alkyl, optionally substituted cycloalkyl, or optionally substituted aryl;
- R2 an R3 are independently OH, —NH2, —OR5, —NHR5, —NR5R5;
- R4 is H, —F, —Cl, —Br, —CN, —OH, —OR5, —NO2, —NH2, —NHR5, —NR5R5;
- and
- each R5 is independently an optionally substituted alkyl, optionally substituted cycloalkyl, or optionally substituted aryl, said method comprising:
- refluxing a fluorescein or rhodamine based compound with hydrazine to form a fluorescein or rhodamine based hydrazide;
- and
- refluxing the fluorescein or rhodamine based hydrazide with a N-alkylimidazole-2-carboxaldehyde to form the Schiff base.
6 more elements
Dependencies are inferred from the claim text.