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US 10,105,289 B2Granted
Biomimetic mineral based endodontic cement composition and uses thereof
AssigneeEssential Dental Systems, Inc.
InventorJason Edward Guzman
Life of this patent
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Abstract
Disclosed are biomimetic mineral based endodontic cement compositions. An endodontic cement comprises a paste A and a paste B. The paste A comprises a pozzolanic cementitious mineral paste and the paste B is a mixture comprising polyanionic polymers, phosphates, cement setting modulators, host-inclusion particles, bioactive glasses, and radiopacity agents suspended in a liquid carrier.
Claims21
An endodontic cement comprising:
- a Paste A, Paste A being a pozzolanic and alkaline mixture of calcined and heat treated magnesium oxide, calcium silicate, dicalcium silicate, tricalcium silicate, metakaolin, calcium hydroxide and zirconium oxide, said mixture in solution with a non-aqueous hydrophilic carrier;
- a Paste B, Paste B being acidic and being capable of modulating cement setting, Paste B comprising a mixture of milled monobasic calcium phosphate, zirconium oxide, wherein said mixture is in solution with the non-aqueous hydrophilic carrier;
- and
- wherein a mixture of Paste A and Paste B hydrates in an aqueous environment to form the endodontic cement, the endodontic cement being radiopaque and antimicrobial when created.
1 more element
A biomimetic endodontic cement comprising:
- a Paste A, Paste A comprising, by weight, about 23-27% calcined and heat treated magnesium oxide, 0.08-1.2% calcium hydroxide, 47-51% zircondium oxide, and 0.08-2.2% bioactive glass in a non-aqueous hydrophilic carrier at about 24-26% by weight;
- and
- a Paste B, Paste B comprising 8-28% milled monobasic calcium phosphate, 50-60% zirconium oxide, 0.001-0.005% polyacrylic acid or PAMAM dendrimeric polymers in a non-aqueous hydrophilic carrier at about 24-26% by weight;
- wherein a mixture of Paste A and Paste B hydrolyzes in an aqueous environment to form the biomimetic endodontic cement, the endodontic cement being biomimetic, radiopaque, and antimicrobial.
1 more element
A biomimetic endodontic cement comprising:
- a Paste A, Paste A comprising by weight about 25% calcined and heat treated magnesium oxide, 0.1-1% calcium hydroxide, 48% zirconium oxide, 25% polyethylene glycol, 0.1-2% bioactive glass, and 0.001-0.005% halloysite clay/chlorohexidine/benzalkonium chloride/benzethonium chloride;
- and
- a Paste B, Paste B comprising by weight about 12% milled monobasic calcium phosphate, 60-63% zirconium oxide, 25% polyethylene glycol, 0.00001-0.00005% halloysite clay/chlorohexidine/benzalkonium chloride/benzethonium chloride, and 0.001-0.005% polyacrylic acid or PAMAM dendrimeric polymers;
- wherein Paste A and Paste B remain separated until use and wherein a mixture of Paste A and Paste B will hydrate in an aqueous environment, creating a robust biomimetic, radiopaque, antimicrobial, and actively remineralizing endodontic cement.
1 more element
Dependencies are inferred from the claim text.