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US 10,098,943 B2Granted
Flavivirus virus like particle
AssigneeVLP Therapeutics, LLC
InventorsWataru Akahata, Ryuji Ueno
Life of this patent
Estimating the term…
Abstract
Provided is a virus like particle comprising one or more flavivirus structural proteins, and a composition or vaccine comprising thereof, its use in the prevention or treatment of flavivirus infection. The flavivirus structural protein contains at least one amino acid alteration in the envelope region. Examples of flavivirus contains dengue virus.
Claims16
A virus like particle comprising a flavivirus envelope protein, wherein said envelope protein comprises an amino acid substitution at position 108 of SEQ ID NO:
- 20, or at a position determined as corresponding to position 108 of SEQ ID NO:
- 20 by alignment.
Dependencies are inferred from the claim text.