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US 10,095,835 B2Granted
Healthcare analysis stream management
AssigneeNant Holdings IP, LLC
InventorPatrick Soon-Shiong
Life of this patent
Estimating the term…
Abstract
Apparatus, systems and methods for pre-processing, analyzing, and storing genomic data through a scalable, distributed analysis system across a network is presented.
Claims27
A genomic analysis system comprising:
- a plurality of sequencing devices configured to pre-process sequence data to generate pre-processed sequence data, the pre-processed sequence data comprising the sequence data and annotations;
- a sequencing device interface configured to acquire pre-processed sequence data from the plurality of sequencing devices, where the sequence data is from a plurality of patients;
- an analysis network;
- and
- a plurality of analysis computer nodes interconnected via the analysis network forming a genomic analysis engine having patient-specific analysis network topologies coupled with the sequencing device interface, and configured to, based on the pre-processed sequence data, process the sequence data from the patients in parallel into patient-specific genome data according to processing routes of the patient-specific analysis network topologies.
2 more elements
A genomic analysis system comprising:
- a plurality of sequencing devices configured to pre-process sequence data to generate pre-processed sequence data, the pre-processed sequence data comprising the sequence data and annotations;
- a sequencing device interface configured to acquire pre-processed sequence data from the plurality of sequencing devices, where the sequence data is from a plurality of patients;
- an analysis network;
- and
- a plurality of analysis computer nodes interconnected via the analysis network forming a genomic analysis engine having patient-specific analysis network topologies coupled with the sequencing device interface, and configured to, based on the pre-processed sequence data, process the sequence data from the patients in parallel into patient-specific genome data according to processing routes of the patient-specific analysis network topologies, wherein a first computer node of the plurality of analysis computer nodes and a second computer node of the plurality of analysis computer nodes are configured into a patient-specific analysis network topology, the first computer node of the plurality of analysis computer nodes applying a first analysis regime to the pre-processed sequence data, and the second computer node of the plurality of analysis computer nodes applying a second analysis regime to the pre-processed sequence data.
2 more elements
A genomic analysis system comprising:
- a plurality of sequencing devices configured to pre-process sequence data to generate pre-processed sequence data, the pre-processed sequence data comprising the sequence data and annotations;
- a sequencing device interface configured to acquire pre-processed sequence data from the plurality of sequencing devices, where the sequence data is from a plurality of patients;
- an analysis network;
- and
- a plurality of analysis computer nodes interconnected via the analysis network forming a genomic analysis engine having patient-specific analysis network topologies coupled with the sequencing device interface, and configured to, based on the pre-processed sequence data, process the sequence data from the patients in parallel into patient-specific genome data according to processing routes of the patient-specific analysis network topologies, wherein a first computer node of the plurality of analysis computer nodes and a second computer node of the plurality of analysis computer nodes are configured into a patient-specific analysis network topology, the first computer node of the plurality of analysis computer nodes operating on a first portion of the pre-processed sequence data, and the second computer node of the plurality of analysis computer nodes operating on a second portion of the pre-processed sequence data.
2 more elements
A genomic analysis system comprising:
- a plurality of sequencing devices configured to pre-process sequence data to generate pre-processed sequence data, the pre-processed sequence data comprising the sequence data and annotations;
- a sequencing device interface configured to acquire pre-processed sequence data from the plurality of sequencing devices, where the sequence data is from a plurality of patients;
- an analysis network;
- and
- a plurality of analysis computer nodes interconnected via the analysis network forming a genomic analysis engine having patient-specific analysis network topologies coupled with the sequencing device interface, and configured to, based on the pre-processed sequence data, process the sequence data from the patients in parallel into patient-specific genome data according to processing routes of the patient-specific analysis network topologies, wherein a first computer node of the plurality of analysis computer nodes and a second computer node of the plurality of analysis computer nodes are, based on an urgency indicated in the pre-processed sequence data, configured into a dedicated topology in analyzing the pre-processed sequence data of a single patient.
2 more elements
A genomic analysis system comprising:
- a plurality of sequencing devices configured to pre-process sequence data to generate pre-processed sequence data, the pre-processed sequence data comprising the sequence data and annotations;
- a sequencing device interface configured to acquire pre-processed sequence data from the plurality of sequencing devices, where the sequence data is from a plurality of patients;
- an analysis network;
- and
- a plurality of analysis computer nodes interconnected via the analysis network forming a genomic analysis engine having patient-specific analysis network topologies coupled with the sequencing device interface, and configured to, based on the pre-processed sequence data, process the sequence data from the patients in parallel into patient-specific genome data according to processing routes of the patient-specific analysis network topologies, wherein a first computer node of the plurality of analysis computer nodes is, based on an urgency indicated in the pre-processed sequence data, configured into a dedicated topology in analyzing the pre-processed sequence data of a single patient.
2 more elements
A genomic analysis system comprising:
- a plurality of sequencing devices configured to pre-process sequence data to generate pre-processed sequence data, the pre-processed sequence data comprising the sequence data and annotations;
- a sequencing device interface configured to acquire pre-processed sequence data from the plurality of sequencing devices, where the sequence data is from a plurality of patients;
- an analysis network;
- and
- a plurality of analysis computer nodes interconnected via the analysis network forming a genomic analysis engine having patient-specific analysis network topologies coupled with the sequencing device interface, and configured to, based on the pre-processed sequence data, process the sequence data from the patients in parallel into patient-specific genome data according to processing routes of the patient-specific analysis network topologies, wherein a first computer node of the plurality of analysis computer nodes is, based on an urgency indicated in the pre-processed sequence data, configured into a dedicated topology in analyzing the pre-processed sequence data.
2 more elements
Dependencies are inferred from the claim text.