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AssigneeIndiana University Research and Technology Corporation
InventorsPeter Muench, Dieter Roessler, Christian Scholz, Barbara Upmeier, Toralf Zarnt
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The present invention concerns a composition of polypeptides suitable for detecting antibodies against Trypanosoma cruzi (T. cruzi) in an isolated biological sample consisting of three polypeptides 1F8, JL7 and Cruzipain. A method of producing a soluble and immunoreactive composition of polypeptides suitable for detecting antibodies against T. cruzi using said composition of polypeptides is also part of the invention. Moreover, the invention concerns a method for detecting antibodies specific for T. cruzi in an isolated sample wherein a composition of said T. cruzi polypeptides is used as well as a reagent kit comprising said composition of T. cruzi polypeptides.
A composition of polypeptides suitable for detecting antibodies agains Trypanosoma cruzi in an isolated biological sample, said composition comprising three recombinantly or synthetically produced polypeptides specific for Trypanosoma cruzi, wherein said polypeptides are selected from the group consisting of SEQ ID NO:1, SEQ ID NO:2 and SEQ ID NO:3.
Dependencies are inferred from the claim text.