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US 10,093,723 B2Granted
Anti-tenascin C antibodies and uses thereof
AssigneeNascient Limited
InventorsKim Suzanne Midwood, Philip Antony Bland-Ward, Nigel Burns, Patrick John Hextall, Susan Rebecca Aungier
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Abstract
There is provided antibodies or antigen-binding fragments, derivatives or variants thereof which are capable of binding to the FBG domain of tenascin-C. There are also provided uses of such antibodies or antigen-binding fragments, derivatives or variants thereof, as well as methods of identifying such antibodies.
Claims25
An anti-fibrinogen-like globe (FBG) domain of tenascin-C antibody or binding fragment comprising a VH region wherein CDRH1 is SEQ ID NO:
- 9, CDRH2 is SEQ ID NO:
- 10, CDRH3 is independently selected from SEQ ID NO:
- 11, 30, 32, 34, 36, 38, 40, 42, 44, and 46, and a VL region wherein a CDRL1 is SEQ ID NO:
- 5, CDRL2 is SEQ ID NO:
- 13 and CDRL3 is SEQ ID NO:
- 14.
3 more elements
Dependencies are inferred from the claim text.