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US 10,093,712 B2Granted
Immunostimulatory compositions and uses thereof
AssigneeSusavion Biosciences, Inc.
InventorsLaura L. Eggink, Valerie Jacobs, Kenneth Hoober
Life of this patent
Estimating the term…
Abstract
The present invention provides novel immune-stimulatory polypeptides, and methods for their use and identification.
Claims8
A branched polypeptide, having a multivalent structure with multiple branches consisting of the amino acid sequence of formula 1:
- B1-[X1-Q-X2-X3-X4-X5-X6-X7-X8-X9-X10-X11]-B2;
- wherein
- X1 is selected from the group consisting of V, E, and A, or X1 is absent;
- X2 is selected from the group consisting of A, N, and G;
- X3 is any amino acid;
- X4 is selected from the group consisting of P and Q;
- X5 is selected from the group consisting of S, R, and C;
- X6 is selected from the group consisting of N, L, G, and K;
- X7 is selected from the group consisting of Q, A, S, and H;
- X8 is selected from the group consisting of H, L, and A;
- X9 is selected from the group consisting of S and T;
- X10 is selected from the group consisting of P and A;
- X11 is selected from the group consisting of R, G, and P;
- and wherein B1 and B2 are independently 1-5 amino acids, or are absent.
11 more elements
A branched polypeptide having a multivalent structure with multiple branches, wherein the multiple branches comprise a polypeptide having the sequence VQATQSNQHTPR (SEQ ID NO:
- 3).
Dependencies are inferred from the claim text.