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US 10,093,653 B2Granted
Vitamin D receptor-coregulator inhibitors
AssigneesUWM Research Foundation, Inc., Women & Infants Hospital of Rhode Island
InventorsAlexander E. Arnold, Preetpal Singh Sidhu, Premchendar Nandhikonda, Rakesh K. Singh
Life of this patent
Estimating the term…
Abstract
Described herein are compounds, pharmaceutical compositions and methods for inhibiting the expression of a vitamin D receptor target gene, inhibiting interactions between the vitamin D receptor and at least one vitamin D receptor coactivator, for treating cancer in a subject, and for inhibiting angiogenesis in a subject.
Claims14
A compound of formula (I):
- wherein:
- m is 1;
- p is 1;
- each R2 and R3 is independently selected from the group consisting of alkoxy and haloalkyl.
1 more element
A compound of formula (I):
- wherein:
- R2 is CF3;
- and
- R3 is methoxy.
1 more element
Dependencies are inferred from the claim text.