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US 10,093,651 B2Granted
Ghrelin O-acyl transferase inhibitors
AssigneeEli Lilly and Company
InventorsChristopher Stanley Galka, Erik James Hembre, Nicholas Allan Honigschmidt, Maria Angeles Martinez-Grau, Gema Ruano Plaza, Almudena Rubio
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Abstract
The present invention provides novel GOAT inhibitors and their salts and pharmaceutical compositions thereof.
Claims17
A compound of formula
- wherein R is selected from —C1-C3 alkyl optionally substituted with —OH;
- —OC1-C4 alkyl;
- pyrazolyl, oxazolyl, thiazolyl, or thiadiazolyl, wherein pyrazolyl, oxazolyl, or thiazolyl each may be optionally substituted one to two times with —CH3;
- pyridinyl, pyridazinyl, or pyrazinyl, wherein each may be optionally substituted with —Cl;
- and phenyl optionally substituted with —OCH3;
- or a pharmaceutically acceptable salt thereof.
3 more elements
Dependencies are inferred from the claim text.