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US 10,093,621 B2Granted
4-oxo-N-(4-hydroxyphenyl)retinamide derivatives as therapeutic agents for the treatment of cancer
AssigneeFondazione IRCCS “Instituto Nazionale dei Tumori”
InventorsMaria Grazia Daidone, Valentina Appierto, Paola Tiberio, Sabrina Dallavalle, Loana Musso, Elisa Niccolini
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Abstract
The present invention relates to a compound having formula (I) below or a pharmaceutically acceptable salt thereof: wherein: X is —COOH or NH2; R is a straight or branched C1-C10 alkylene chain; and R1 is H, straight or branched C1-C10 alkyl, aryl, or R2CO— wherein R2 is straight or branched C1-C10 alkyl, for use as antitumoral agents.
Claims18
A compound of the following formula (I), or a pharmaceutically acceptable salt thereof:
- wherein:
- X is —COOH or NH2;
- R is a straight or branched C1-C10 alkylene chain;
- and
- R1 is H, straight or branched C1-C10 alkyl, aryl, or R2CO—, wherein R2 is straight or branched C1-C10 alkyl.
2 more elements
Dependencies are inferred from the claim text.