Polymeric nanoparticles and a process of preparation thereof
AssigneeNanoproteagen
InventorHarpal Singh
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Abstract
The present invention relates to the field of nanotechnology, in particular, to the production of biodegradable polymeric nanoparticles. The present invention provides a biodegradable polymeric nanoparticle made up of a block copolymer and a process for producing the same. The nanoparticles are produced without the use of any emulsifiers and have a size ranging from 30-120 nm. The methods of controlling the drug loading capacity are disclosed along with the process of producing entity-loaded nanoparticles. Compositions comprising the nanoparticles and their use in therapeutics, diagnostics and theranostics are also disclosed.
Claims25
A biodegradable polymeric nanoparticle formed of a block copolymer consisting essentially of poly(lactic acid) (PLA) chemically conjugated to a hydrophilic-hydrophobic block copolymer, wherein said hydrophilic-hydrophobic block copolymer consists essentially of PEG-PPG-PEG, the biodegradable nanoparticle is formed of the tetra block copolymer PLA-PEG-PPG-PEG, and the polymer of the biodegradable polymeric nanoparticle consists of one tetrablock copolymer.
Dependencies are inferred from the claim text.