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US 10,092,593 B2Granted
Citrate-rich calcium-magnesium supplement and uses thereof
AssigneeBoard of Regents, The University of Texas System
InventorsCharles Y. C. Pak, Khashayar Sakhaee, Orson W. Moe
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Abstract
Disclosed is an effervescent preparation of calcium and magnesium with additional citric acid in a defined ratio. Also disclosed is the use of these compositions to raise cardioprotective citrate and magnesium in serum to help prevent heart attacks from calcium supplements, and to provide bioavailable calcium and magnesium to prevent osteoporosis-related fractures and low blood magnesium from the use of proton pump inhibitors.
Claims11
A method of reducing calciprotein particle (CPP) formation in an animal in need thereof, the method comprising:
- administering to the animal a composition comprising:
- from about 250 mg calcium to about 600 mg of calcium,
- from about 70 mg magnesium to about 175 mg of magnesium,
- at least 10 meq of citrate excess, and
- at least 20 meq of total soluble citrate,
- wherein the Ca/citrate molar ratio is from 0.4 to 0.7 and
- wherein the CPP formation is reduced.
4 more elements
Dependencies are inferred from the claim text.