Suppositories comprising cannabinoids
AssigneeAxim Biotechnologies, Inc.
InventorsLekhram Changoer, George Anastassov
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Abstract
This invention relates to a suppository composition comprising cannabinoids. The suppository composition is formulated for easy absorption through mucosal membrane. The suppository as provided herein is useful for administration of cannabinoids in patients with nausea, vomiting, other conditions preventing swallowing, or conditions wherein suppository administration is required. Methods to manufacture the suppository composition are provided. Methods to treat pain, nausea, post-operative ileus and/or inflammatory bowel diseases using the suppository according to this invention are also provided.
Claims16
A suppository composition comprising:
- at least one cannabinoid at 0.1% to 50% by weight of the total composition;
- at least one sugar alcohol or sugar at 15% to 25% by weight of the total composition;
- at least one fatty base suitable for suppository formulation selected from the group consisting of glycerol ricinoleate, hydrogenated coco-glycerin, and ceteareth-25 at 60% to 80% by weight of the total composition;
- and
- at least one non-ionic surfactant selected from the group consisting of ceteareth-15 and ceteareth-17 at 2% to 10% by weight of the total composition,
- wherein the at least one cannabinoid is encapsulated into hyaluronic acid derivatives and tocopherol nanolattice, and
- wherein the composition is packaged in a suppository mold.
Dependencies are inferred from the claim text.