Implantable cellular and biotherapeutic agent delivery canister
AssigneeNanoVault Medical LLC
InventorsWillard W. Hennemann, Bryan L. Steelman, Thomas J. Webster
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Abstract
The invention relates to a metallic, nanoporous canister used to encapsulate cellular and/or biotherapeutic agents. The device is biocompatible and functions to wholly isolate a therapeutically active agent and/or cells therein. Their implantation, and survival in vivo, permits the local or systemic diffusion of their encapsulated cellular and/or biomolecular and therapeutics factors with the potential to promote repair of damaged or degenerated tissues in mammalian hosts, primarily humans.
Claims19
An implantable canister for containing and delivering metabolically active agents, comprising:
- a metallic shell having nanoscale through-porous membrane characteristics including a bicontinuous morphology defining a first major surface, a second major surface, and an interior chamber between the first major surface and second major surface;
- and
- means allowing fluid communication with the interior chamber.
The canister of claim7 further comprising a plurality of internal baffles wherein the internal raised channels are separate from each other.
An implantable canister for containing and delivering metabolically active agents, comprising:
- a metallic shell having nanoscale through-porous membrane characteristics including a bicontinuous morphology defining a first major surface, a second major surface, a side surface separating the first major surface and the second major surface, and an interior chamber between the first major surface and second major surface;
- and
- means allowing fluid communication with the interior chamber.
Dependencies are inferred from the claim text.