Non-invasive in situ glucose level sensing using electromagnetic radiation
AssigneeAdvantest Corporation
InventorYang Shang
Life of this patent
Estimating the term…
Abstract
System and method of using electromagnetic radiation signals to non-invasively test a glucose level in a subject. During operation, an incident beam of Terahertz waves is generated and projected onto the surface of the eyeball, which is naturally reflected by a tear layer. The reflected Terahertz waves are detected and characterized to determine the reflection characteristics of the tear layer, e.g., an axial ratio of reflection coefficients in two polarization orientations. Provided with the determined axial ratio and according to a predetermined correlation among axial ratio, tear glucose level and blood glucose level, the current blood glucose level in the subject can be derived and presented to a user.
Claims19
A method of determining glucose levels, said method comprising:
- irradiating first electromagnetic waves onto an eyeball of a subject;
- detecting second electromagnetic waves in two orthogonal polarization orientations produced by said first electromagnetic waves being reflected from said eyeball;
- and
- determining said glucose level in said subject based on characteristics of said first electromagnetic waves and said second electromagnetic waves and further based on a predetermined correlation between a tear glucose level and a blood glucose level, wherein second electromagnetic waves originate by first electromagnetic waves reflected from a tear film covering said eyeball.
A method of determining a glucose level in a subject, said method comprises:
- at a first predetermined position relative to an eyeball of said subject, irradiating first Terahertz waves onto said eyeball;
- at a second predetermined position relative to said eyeball, detecting second Terahertz waves in two orthogonal polarization orientations produced by said first Terahertz waves being reflected from a tear layer covering said eyeball;
- and
- automatically determining said glucose level in said subject based on characteristics of said second Terahertz waves relative to said first Terahertz waves and further based on a predetermined correlation between tear glucose level and blood glucose level.
A method of detecting a glucose level of a subject, said method comprising:
- irradiating first electromagnetic waves onto an eyeball of said subject;
- determining reflection characteristics in two orthogonal polarization orientations of a tear layer covering said eyeball with respect to said first electromagnetic waves;
- and
- determining the glucose level in said subject based on said reflection characteristics of said tear layer with respect to said first electromagnetic waves and further based on a predetermined correlation between tear glucose level and blood glucose level.
Dependencies are inferred from the claim text.