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US 10,092,181 B2Granted
Method of imaging multiple retinal structures
AssigneeUniversity of Rochester
InventorsQiang Yang, Ethan Andrew Rossi
Life of this patent
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Abstract
Methods and apparatus for imaging multiple retinal structures and montaging of multiple retinal images are provided. The method involves cross-correlating images from different imaging channels to compensate for intra-frame distortion due to retinal movement during image acquisition, and conducting a second cross-correlation to filter out any motion artifacts in the images. The resultant images are combined to generate a composite image. The method also involves controlling light directed on the retina spatially and temporally.
Claims17
A method of imaging multiple retinal structures comprising:
- direct light on a portion of the retina to achieve irradiance;
- acquire a first image frame and register successive image frames of a portion of the retina from a first imaging channel, and simultaneously acquire and co-register second image frames of the portion of the retina from a second, different imaging channel;
- divide the first image frame and each successive image frame into corresponding multiple strips, and cross-correlate each successive image frame strip with a corresponding first image frame strip to compensate for intra-frame distortion due to retinal movement during image acquisition, and apply these strip motions to the second image frames and co-register the second image strips;
- re-divide the registered successive image frames into second strips, and conduct a second cross-correlation of each corresponding second strip, thereby filtering out any motion artifacts in the registered images and register the first images, and
- combine the final first images and generate a composite image for the first imaging channel, and co-register and combine final second images and generate a composite image for the second imaging channel.
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