Raising and diagnosing of serotonin level
AssigneeGut Guide Oy
InventorsAnnika Mayra-Makinen, Eveliina Munukka
Life of this patent
Estimating the term…
Abstract
The invention is based on a correlation observed between serotonin level and intestinal flora. The invention relates to a relative proportion of bifidobacteria in the intestine and in particular to a product increasing the ratio of bifidobacteria to Clostridia, to be used for raising the serotonin level. The invention also relates to a method for estimating a health risk associated with serotonin depletion by determining a relative proportion between bifidobacteria or Clostridia in the intestine or their ratio to one another. The invention further relates to a method for selecting a form of therapy for raising the serotonin level by determining a relative proportion between bifidobacteria or Clostridia in the intestine or their ratio to one another.
Claims4
A method for estimating a human target's health risk associated with serotonin depletion, comprising determining the percentage of bifidobacteria and clostridia in total fecal microbiota of a fecal sample obtained from the target using 16sRNA hybridization, DNA staining, and/or flow cytometry, and calculating a ratio of said bifidobacteria to said clostridia in the sample, wherein the calculated ratio higher than 1 indicates that the target's health risk is not increased.
A method for estimating a human target's health risk associated with serotonin depletion, comprising determining the percentage of bifidobacteria and clostridia in total fecal microbiota of a fecal sample obtained from the target using 16sRNA hybridization, DNA staining, and/or flow cytometry, and calculating a ratio of said bifidobacteria to said clostridia in the sample, wherein the calculated ratio of less than 1 indicates that the target's health risk is increased.
A method for selecting a form of therapy for raising the serotonin level in a human target, comprising determining the percentage of bifidobacteria and clostridia in total fecal microbiota of a fecal sample obtained from the target using 16sRNA hybridization, DNA staining, and/or flow cytometry, and calculating a ratio of said bifidobacteria to said clostridia in the sample, wherein the calculated ratio of less than 1 indicates that the form of therapy to be selected for raising the serotonin level in the target comprises administering to the target a product which increases the relative proportion of bifidobacteria to clostridia in the intestine of the target.
A method for raising serotonin level in a human target, in which method the target in need of this kind of treatment has a ratio of bifidobacteria to clostridia of less than 1 in a fecal sample obtained from the target using 16sRNA hybridization, DNA staining, and/or flow cytometry, and the method comprises administering a potent amount of a product which increases the relative proportion of bifidobacteria to clostridia in the intestine of the target for raising the serotonin level in the target.
Dependencies are inferred from the claim text.