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US 10,087,453 B2Granted
Modified diatoms for biofuel production
AssigneeCellectis
InventorsPhilippe Duchateau, Fayza Daboussi, David Sourdive, Jean-Charles Epinat
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Abstract
The invention provides engineered diatoms and methods of producing oil using diatoms. The invention also provides methods of modifying the lipids quantity and/or quality produced by diatom organisms through genome engineering. Also provided are oils, fuels, oleochemicals, chemical precursors, and other compounds manufactured from such modified diatoms.
Claims20
A diatom strain, which has been genetically modified in a gene involved in lipid metabolism selected from the group consisting of:
- delta-12 desaturase, omega-3 desaturase, palmitoyl protein thioesterase and Enoyl ACP reductase, wherein said gene has been inactivated, and wherein said diatom strain produces an increased amount, storage and/or quality of lipids in comparison with its wild type, and has a lipid content of at least 40% of its dry weight.
Dependencies are inferred from the claim text.