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US 10,086,352 B2Granted
Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
AssigneeVERO Biotech Inc.
InventorsDavid H. Fine, David R. Rounbehler, Gregory Vasquez, Brian Johnson
Life of this patent
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Abstract
A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.
Claims11
A system for generating a therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal comprising:
- a pressure regulator diffusing gaseous nitrogen dioxide into an air flow wherein the air flow is configured to be between 5 to 60 liters per minute;
- a receptacle configured to attach to the pressure regulator, the receptacle including an inlet, an outlet, and a surface-active material coated with an aqueous solution of an antioxidant, wherein the inlet is configured to receive the air flow and fluidly communicate the flow to the outlet through the surface-active material to convert the gaseous nitrogen dioxide to nitric oxide at ambient temperature.
Dependencies are inferred from the claim text.