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US 10,086,037 B2Granted
Compositions and methods to prevent cancer with cupredoxins
OwnerTapas Das Gupta, Ananda Chakrabarty +2inventors
InventorsTapas Das Gupta, Ananda Chakrabarty, Craig Beattie, Tohru Yamada
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Abstract
The present invention discloses methods and materials for delivering a cargo compound into a cancer cell. Delivery of the cargo compound is accomplished by the use of protein transduction domains derived from cupredoxins. The cargo compound may be a nucleic acid and specifically a DNA, RNA or anti-sense. The invention further discloses methods for treating cancer and diagnosing cancer.
Claims11
A complex comprising:
- an isolated peptide consisting of SEQ ID NO:
- 25 coupled to a cargo compound and wherein the isolated peptide can selectively enter mammalian cancer cells.
Dependencies are inferred from the claim text.