Lactonase enzymes and methods of using same

A composition comprising a variant lactonase enzyme comprising an amino acid substitution as compared to SEQ ID NO:1, wherein said amino acid substitution is at a position selected from 17, 32, 34, 35, 41, 50, 62, 66, 68, 69, 70, 74, 76, 77, 79, 80, 81, 83, 84, 114, 120, 122, 123, 127, 132, 136, 139, 155, 162, 164, 184, 185, 188, 189, 192, 193, 195, 218, 221, 222 and 244, wherein said variant lactonase enzyme retains lactonase activity and is at least 95% identical to SEQ ID NO:1.