Extraction separation using magnetic beads
AssigneeGE Healthcare Bio-Sciences AB
InventorsNils Norrman, Pierre Le Greves
Life of this patent
Estimating the term…
Abstract
A method for purifying a substance in a solution in a simple streamlined process using a magnetic porous particle. For easy small scale purification of a substance, the magnetic porous particle is coated with either a hydrophilic or hydrophobic liquid and transferred into a second liquid containing the substance under conditions which allow said substance to partition into the first liquid within said magnetic porous particle. Finally the magnetic porous particle is removed from said second liquid, wherein the first and second liquid are substantially immiscible and the partition coefficient P of the substance between the first and second liquid is greater than 1.
Claims26
A method of extracting a substance from a liquid, the method comprising;
- contacting a porous particle comprising a superparamagnetic or ferromagnetic material with a first liquid;
- transferring said porous particle to a second liquid containing a substance under conditions to allow said substance to partition into said first liquid within said porous particle;
- and
- separating the porous particle from said second liquid,
- wherein the first and second liquid are substantially immiscible and the partition coefficient P of the substance between the first and second liquid is greater than 1.
Dependencies are inferred from the claim text.