US 10,036,037 B2 · Insect inhibitory proteins

Abstract

Pesticidal proteins exhibiting toxic activity against Coleopteran and Lepidopteran pest species are disclosed, and include, but are not limited to, TIC2421 TIC3008, and TIC7055. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran and Coleopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Coleopteran and Lepidopteran species pests using any of the TIC2421, TIC3008, and TIC7055 pesticidal proteins are also provided.

Claims21

Dependent claims

A recombinant nucleic acid molecule comprising a heterologous promoter operably linked to a polynucleotide segment encoding a pesticidal protein, wherein:

said pesticidal protein comprises the amino acid sequence selected from the group consisting of SEQ ID NO:8, SEQ ID NO:12, SEQ ID NO:4, and SEQ ID NO:28.

Dependencies are inferred from the claim text.

Facts

Application

15/230,112Filed 5 Aug 2016 · us provisional application

Priority

18 Aug 2015

Published

US 2017/0137842 A118 May 2017

Granted

31 Jul 2018

Term ends

Not estimatedThe source records don’t support an estimate.

Classification15 codes

A01N 63/50
Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances…:…
A01N 37/46
Containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton…
C07K 14/195
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof: from bacteria
C07K 14/325
From Bacillus: bacillus thuringiensis crystal peptides, i.e. delta-endotoxins

Insect inhibitory proteins

Life of this patent

Insect inhibitory proteins

Life of this patent

Abstract

Claims21