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US 10,034,929 B2Granted
RNA interference functions as an antiviral immunity in mammals
AssigneeThe Regents of the University of California
InventorsShou-Wei Ding, Yang Li
Life of this patent
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Abstract
The disclosure provides recombinant viral vectors and attenuated viruses and viral vaccines comprising a virus lacking a functional viral RNA suppressor of host RNAi.
Claims11
A method for reducing likelihood of a subsequent infection by a virus in a mammal, the method comprising administering to the mammal an attenuated form of the virus that lacks a functional viral suppressor of RNA interference (VSR), wherein administration of the attenuated form of the virus that lacks a functional VSR confers resistance against subsequent infection by the virus.
Dependencies are inferred from the claim text.