Medical tissue-marker and manufacturing method for the same
AssigneeNational University Corporation Chiba University
InventorsHideki Hayashi, Hirosuke Hatayama, Masanori Fujinami, Taro Toyota
Life of this patent
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Abstract
A medical tissue-marker which enables the identification of a location even from the outside of an organ, can remain topical over a long period, and enables the easy identification of a marked location within the whole organ; also a manufacturing method for the medical tissue-marker. The medical tissue-marker includes a vesicle formed by the synthesis of a phospholipid and a near infrared fluorescent dye, and an emulsion formed by the synthesis of the phospholipid and an X-ray contrast medium, and has agglomerated clusters wherein the vesicle and the emulsion are contained in a hydrophilic solvent and a plurality of capsules are formed by use of an emulsifier.
Claims2
A medical tissue-marker comprising:
- a plurality of capsules formed and aggregated by an emulsifier, each capsule containing a hydrophilic solvent, a vesicle and an emulsion,
- wherein the vesicle is formed by combining a phospholipid and a near-infrared fluorescent dye, the emulsion is formed by combining the phospholipid and an X-ray contrast medium, the X-ray contrast medium is also provided outside of the capsules, the phospholipid is phosphatidylcholine and the X-ray contrast medium is a member selected from the group consisting of iodobenzene and derivatives thereof and barium salt and mixtures thereof.
Dependencies are inferred from the claim text.