Biomarkers for diagnosing ischemia
AssigneeThe Regents of the University of California
InventorsFrank Sharp, Glen C Jickling
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Abstract
The present invention provides methods and compositions for diagnosing and predicting the occurrence of ischemia. For example, the present invention provides methods and compositions for diagnosing and predicting the risk and cause of transient neurological events (TNE) as ischemic or non-ischemic.
Claims11
A kit comprising a microarray attached to nucleic acids that hybridize to ischemia biomarkers comprising UBE2J1, ELAVL3, FCGR2B, BLVRA, JMJD6, DDAH2, PTRH2, CARD16, CAV1, ZNF608, NDUFB3, SLC22A4, PCMT1, CACNA1A, CASP1, LOC100129105, AK5, DIP2A, ETS1, CCND3, GNE, BCL9L, SPATA5 and LBH, wherein the microarray comprises 1000 or fewer hybridizing nucleic acids, and further comprising buffers, salts and/or other reagents to facilitate amplification and/or detection reactions for determining the expression levels of ischemia biomarkers.
Dependencies are inferred from the claim text.