Back to results
US 10,010,436 B2Granted
Polymeric stent and methods of manufacturing the same
AssigneeDotter Intellectual Pte, Ltd.
InventorHyung-Il Kim
Life of this patent
Estimating the term…
Abstract
A method of manufacturing a polymeric stent by forming a pattern on a polymer tube with a laser, where the pattern formed on the polymer tube comprises a plurality of repeating units comprising a plurality of unit cells, each having a V-shaped configuration and polymeric stents formed by the methods. The pattern may be formed on the polymer tube (e.g., polylactic acid tube) using a second harmonic generator laser in which a wavelength ranging from 940 nm to 1552 nm is converted.
Claims9
A polymeric stent manufactured by a method comprising:
- forming a pattern on a polymer tube with a laser;
- wherein the pattern formed on the polymer tube comprises a plurality of repeating units comprising a plurality of unit cells, wherein each unit cell has a V-shaped configuration and comprises a first hinge portion having a first end and a second end, wherein the first hinge portion is bent inwardly to the unit cell and a second hinge portion having a first end and a second end, wherein the second hinge portion is facing the first hinge portion and bent outwardly from the unit cell;
- and a linker portion extended outwardly from a bent portion of the second hinge portion;
- wherein the repeating units are disposed such that an end of a linker portion of one repeating unit is connected to a bent portion of a first hinge portion of an adjacent repeating unit, or
- the first end of a first hinge portion and the first end of a second hinge portion of one repeating unit are connected to an end of a first hinge portion and an end of a second hinge portion of the adjacent repeating unit, respectively;
- wherein the plurality of repeating units are manufactured from a biodegradable polymer;
- wherein the laser has a pulse width of 1 fs to 900 fs and a repetition rate of 2 kHz to 200 kHz;
- wherein the thickness of the unit cell and the strut of the linker portion is 80 to 120 μm;
- wherein a polydispersity index of the polymeric stent ranges from 1 to 2;
- wherein the pattern is formed on the polymer tube using a second harmonic generator laser in which a wavelength ranging from 940 nm to 1552 nm is converted;
- and
- wherein the polymeric stent has a target diameter and is capable of withstanding expansion of up to 1 mm beyond the target diameter without forming fractures or cracks.
9 more elements
A polymeric stent, comprising:
- a pattern of repeating units comprising a plurality of unit cells, wherein each unit cell has a V-shaped configuration and comprises a first hinge portion having a first end and a second end, wherein the first hinge portion is bent inwardly to the unit cell and a second hinge portion having a first end and a second end, wherein the second hinge portion is facing the first hinge portion and bent outwardly from the unit cell;
- and a linker portion extended outwardly from a bent portion of the second hinge portion;
- wherein the repeating units are disposed such that an end of a linker portion of one repeating unit is connected to a bent portion of a first hinge portion of an adjacent repeating unit, or the first end of a first hinge portion and the first end of a second hinge portion of one repeating unit are connected to an end of a first hinge portion and an end of a second hinge portion of the adjacent repeating unit, respectively;
- wherein the repeating units comprising a plurality of unit cells are manufactured from a biodegradable polymer;
- wherein the thickness of the unit cell and the strut of the linker portion is 80 to 120 μm;
- wherein the pattern is formed on a polymer tube using a laser having a pulse width of 1 fs to 900 fs and a repetition rate of 2 kHz to 200 kHz;
- and
- wherein a polydispersity index of the polymeric stent, in which the pattern is formed, ranges from 1 to 2;
- wherein the pattern is formed on the polymer tube using a second harmonic generator laser in which a wavelength ranging from 940 nm to 1552 nm is converted;
- and
- wherein the polymeric stent has a target diameter and is capable of withstanding expansion of up to 1 mm beyond the target diameter without forming fractures or cracks.
8 more elements
A polymeric stent, comprising:
- a pattern of repeating units comprising a plurality of unit cells, wherein each unit cell has a V-shaped configuration and comprises a first hinge portion having a first end and a second end, wherein the first hinge portion is bent inwardly to the unit cell and a second hinge portion having a first end and a second end, wherein the second hinge portion is facing the first hinge portion and bent outwardly from the unit cell;
- and a linker portion extended outwardly from a bent portion of the second hinge portion;
- wherein the repeating units are disposed such that an end of a linker portion of one repeating unit is connected to a bent portion of a first hinge portion of an adjacent repeating unit, or the first end of a first hinge portion and the first end of a second hinge portion of one repeating unit are connected to an end of a first hinge portion and an end of a second hinge portion of the adjacent repeating unit, respectively;
- wherein the repeating units comprising a plurality of unit cells are manufactured from a biodegradable polymer;
- wherein the thickness of the unit cell and the strut of the linker portion is 80 to 120 μm;
- wherein the pattern is formed on a polymer tube using a laser having a pulse width of 1 fs to 900 fs and a repetition rate of 2 kHz to 200 kHz;
- and
- wherein a variation in average molecular weight represented by the following Equation 2 is 20% or less:
- Variation
-
-
- in
-
-
- Average
-
-
- Molecular
-
-
-
- Weight
-
-
- (
- %
- )
- =
- C
- -
- D
- C
- ×
- 100
- (
- Equation
-
-
- 2
- )
- wherein, in Equation 2,
- C is an average molecular weight of a polymeric stent before a pattern is formed;
- and
- D is an average molecular weight of the polymeric stent after the pattern is formed;
- wherein the pattern is formed on the polymer tube using a second harmonic generator laser in which a wavelength ranging from 940 nm to 1552 nm is converted;
- and
- wherein the polymeric stent has a target diameter and is capable of withstanding expansion of up to 1 mm beyond the target diameter without forming fractures or cracks.
44 more elements
Dependencies are inferred from the claim text.